Biological bad luck blamed in two-thirds of cancer cases

Biological bad luck blamed in two-thirds of cancer cases
By Will Dunham | Reuters – Thu, 1 Jan, 2015

WASHINGTON (Reuters) – Plain old bad luck plays a major role in determining who gets cancer and who does not, according to researchers who found that two-thirds of cancer incidence of various types can be blamed on random mutations and not heredity or risky habits like smoking.

The researchers said on Thursday random DNA mutations accumulating in various parts of the body during ordinary cell division are the prime culprits behind many cancer types.

They looked at 31 cancer types and found that 22 of them, including leukemia and pancreatic, bone, testicular, ovarian and brain cancer, could be explained largely by these random mutations – essentially biological bad luck.

The other nine types, including colorectal cancer, skin cancer known as basal cell carcinoma and smoking-related lung cancer, were more heavily influenced by heredity and environmental factors like risky behavior or exposure to carcinogens.

Overall, they attributed 65 percent of cancer incidence to random mutations in genes that can drive cancer growth.

https://ca.news.yahoo.com/biological-bad-luck-blamed-two-thirds-cancer-cases-190103087.html