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A New COVID Variant Featuring Increased Transmissibility Strikes the UK

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the staff of the Ridgewood blog

Ridgewood NJ, according to  Johns Hopkins Center for Health Security a new SARS-CoV-2 variant has come to prominence in the UK, and there are concerns that it has increased transmissibility compared to other variants. The new variant was originally labeled as VUI-202012/01—variant under investigation; the first VUI in December 2020— and subsequently updated to VOC-202012/01—variant of concern. Other analysis labels the variant B.1.1.7. The variant is characterized by at least 17 specific mutations, including 8 for the spike protein, which attaches to the ACE2 receptor and allows the virus to enter cells. Preliminary research indicates that the change could make the virus more transmissible. UK researchers identified the mutations in specimens from as far back as September based on analysis of genetic sequencing data, and the variant “circulated at very low levels…until mid-November.” UK health officials began investigating the new variant in November, after increasing social distancing restrictions were not having the intended effect in Kent County in southeast England. Health officials subsequently identified widespread community transmission of the variant in nearby London and Essex County.

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