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AstraZeneca’s COVID-19 vaccine Gets Emergency Approval in the UK

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the staff of the Ridgewood blog

London UK, AstraZeneca’s COVID-19 vaccine has been approved for emergency supply in the UK, with the first doses being released today so that vaccinations may begin early in the New Year. The approval was hailed by  Prime Minister Boris Johnson as “a triumph for British science.”

The shot is expected to be rolled out next week and would be added to the Pfizer-BioNTech vaccine which has so far been given to 600,000 people in the U.K., according to government statistics.

The UK Medicines and Healthcare products Regulatory Agency (MHRA) has provided authorisation for emergency supply of COVID-19 Vaccine AstraZeneca, formerly AZD1222, for the active immunisation of individuals 18 years or older. The authorisation recommends  two doses administered with an interval of between four and 12 weeks. This regimen was shown in clinical trials to be safe and effective at preventing symptomatic COVID-19, with no severe cases and no hospitalisations more than 14 days after the second dose.

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A New COVID Variant Featuring Increased Transmissibility Strikes the UK

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the staff of the Ridgewood blog

Ridgewood NJ, according to  Johns Hopkins Center for Health Security a new SARS-CoV-2 variant has come to prominence in the UK, and there are concerns that it has increased transmissibility compared to other variants. The new variant was originally labeled as VUI-202012/01—variant under investigation; the first VUI in December 2020— and subsequently updated to VOC-202012/01—variant of concern. Other analysis labels the variant B.1.1.7. The variant is characterized by at least 17 specific mutations, including 8 for the spike protein, which attaches to the ACE2 receptor and allows the virus to enter cells. Preliminary research indicates that the change could make the virus more transmissible. UK researchers identified the mutations in specimens from as far back as September based on analysis of genetic sequencing data, and the variant “circulated at very low levels…until mid-November.” UK health officials began investigating the new variant in November, after increasing social distancing restrictions were not having the intended effect in Kent County in southeast England. Health officials subsequently identified widespread community transmission of the variant in nearby London and Essex County.

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Europe debates whether to reopen schools and how to best protect students and teachers

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the staff of the Ridgewood blog
Ridgewood NJ, according to Johns Hopkins Center for Health Security, like most of the rest of the world, European countries have been debating whether to reopen schools and how to best protect students and teachers. Public Health England conducted enhanced surveillance among schools that reopened between June 1-July 31 in order to provide better information regarding SARS-CoV-2 transmission risk in school settings. While approximately 80% of schools remained open in some capacity during the UK lockdown to support certain priority groups (eg, children of healthcare workers), the vast majority of children did not attend in-person classes. In June, the number of students attending schools increased from 475,000 to more than 1.6 million.

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