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Dementia-preventing nasal spray goes to human trials

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A novel nasal spray combines a common antibiotic with a well-known antioxidant and human trials are set to begin soon

the staff of the Ridgewood blog

Ridgewood NJ, a novel nasal spray designed to prevent the neurodegeneration associated with dementia has shown promising results in mouse studies. The spray is a combination of two pre-existing drugs. Mice with neurodegenerative diseases showed improved cognition and less accumulation of toxic proteins in the brain after the spray was intranasally administered five times a week for a month. The combination of drugs was more effective at preventing neurodegeneration than each drug by itself. Human trials will start soon in several countries, including Japan and the US.

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Pfizer testing pill designed to stop Covid-19

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the staff of the Ridgewood blog

Ridgewood NJ, Pfizer has developed a pill designed to stop Covid-19. It is now starting human trials on the drug, which showed no significant risks or safety concerns during its animal studies. The human trials will be split into three phases and run for 145 days. Another 28 days will be added to the trial period for screening and dosing. The drug attacks the spine of the SARS-CoV-2 virus and stops it from replicating in the nose, throat, and lungs. It is classed as a protease inhibitor.