Category: Coronavirus

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Moderna’s COVID-19 Vaccine 94.5% Effective !

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the staff of the Ridgewood blog

CAMBRIDGE, Mass.,  Moderna, Inc. (Nasdaq: MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines to create a new generation of transformative medicines for patients, today announced that the independent, NIH-appointed Data Safety Monitoring Board (DSMB) for the Phase 3 study of mRNA-1273, its vaccine candidate against COVID-19, has informed Moderna that the trial has met the statistical criteria pre-specified in the study protocol for efficacy, with a vaccine efficacy of 94.5%. This study, known as the COVE study, enrolled more than 30,000 participants in the U.S. and is being conducted in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and the Biomedical Advanced Research and Development Authority (BARDA), part of the Office of the Assistant Secretary for Preparedness and Response at the U.S. Department of Health and Human Services.

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Reader repeats , “New Jersey should have been well prepared to protect patients in nursing homes from the coronavirus. Instead, nearly half of all the state’s coronavirus deaths have been at nursing homes and assisted living facilities.”

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“Thank you Assemblyman Robert Auth on behalf of those poor 11 childrens’ families.
The Ridgewood Blog was covering The Wanague Curse for almost two years now and it’s time for MJDOH and its cronies to be held responsible for those poor 11 innocent souls…..
“Considering all the state and federal reports, and recommendations from Murphy’s own administration, New Jersey should have been well prepared to protect patients in nursing homes from the coronavirus. Instead, nearly half of all the state’s coronavirus deaths have been at nursing homes and assisted living facilities.” ”

https://theridgewoodblog.net/the-murphy-administration-ignored-earlier-lessons-as-the-pandemic-spread-in-nursing-homes/

 

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Civilian Defense and Disaster Control Act Requires That Closed Businesses and Services must be Compensated

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the staff of the Ridgewood blog

Montville NJ,  State Senator Joe Pennacchio is calling on Governor Murphy to uphold the Civilian Defense and Disaster Control Act often cited by the Governor in shuttering businesses.

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U.S. Food and Drug Administration Grants Emergency Use Authorization for Eli Lilly COVID Antibody Drug

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the staff of the Ridgewood blog

INDIANAPOLIS  IN, The U.S. Food and Drug Administration (FDA) today granted Emergency Use Authorization (EUA) for Eli Lilly and Company’s (NYSE: LLY) investigational neutralizing antibody bamlanivimab (LY-CoV555) 700 mg. Bamlanivimab is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test, who are at high risk for progressing to severe COVID-19 and/or hospitalization. Bamlanivimab should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion.

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PFIZER AND BIONTECH ANNOUNCE VACCINE CANDIDATE AGAINST COVID-19 ACHIEVED 90% SUCCESS RATE

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Vaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysis

Analysis evaluated 94 confirmed cases of COVID-19 in trial participants

Study enrolled 43,538 participants, with 42% having diverse backgrounds, and no serious safety concerns have been observed; Safety and additional efficacy data continue to be collected

Submission for Emergency Use Authorization (EUA) to the U.S. Food and Drug Administration (FDA) planned for soon after the required safety milestone is achieved, which is currently expected to occur in the third week of November

Clinical trial to continue through to final analysis at 164 confirmed cases in order to collect further data and characterize the vaccine candidate’s performance against other study endpoints

the staff of the Ridgewood blog

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Farmed Minks Capable of Transmitting SARS-CoV-2 to humans

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the staff of the Ridgewood blog
Copenhagen Denmark, according to Johns Hopkins Center for Health Security , Danish Prime Minister Mette Frederiksen announced this week that Denmark will cull all mink at farms across the country, including those used for breeding, in order to mitigate the risk of zoonotic transmission of SARS-CoV-2. Mink have been identified as animals capable of transmitting SARS-CoV-2 to humans, and there have been multiple examples of outbreaks among mink populations in Denmark and elsewhere. Mink are bred in Denmark and other countries for their pelts.

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ELI LILLY monoclonal antibody treatment for COVID Shows Promise

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the staff of the Ridgewood blog
Ridgewood NJ, according to Johns Hopkins Center for Health Security , ELI LILLY A recent study published in the New England Journal of Medicine last week reported that convalescent plasma derived monoclonal antibody treatment (LY-CoV555), developed by Eli Lilly, showed clinical benefit in patients. The study found that patients experienced decreased viral loads and severity, and had no serious adverse effects in outpatients. The phase II trial involved outpatients that had mild to moderate COVID-19. A total of 452 patients participated, receiving either low, medium or high concentration of the antibody, or placebo. Researchers measured the change in viral load after 11 days of treatment, and the study has reported on interim findings. Patients receiving the medium dose (2800 mg) had about a 3 fold reduction in viral load. Differences among placebo and treatment groups were non-significant and smaller for both the low and the high dosage categories. However, patients receiving any antibody dose had lower symptom severity as well as lower hospitalization rates than placebo. Additionally, the percentage of adverse events was similar across treatment and placebo groups.

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CDC Study found that mask use increased from 78% in April to 89% in June, but Other crucial mitigation measures, stagnated or declined

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the staff of the Ridgewood blog

Ridgewood NJ, according to Johns Hopkins Center for Health Security a recent CDC study published in the MMWR assessed self-reporting of recommended behaviors to mitigate SARS-CoV-2 transmission, including mask-wearing, hand washing, social distancing, and staying home when sick. The Data Foundation COVID Impact Survey collected national data on reported mitigation behaviors from April to June among adults.

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The Widespread Lockdown Policy has been a Devastating Public Health Mistake !

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the staff of the Ridgewood blog

Great Barrington MA, Jay Bhattacharya is a Professor of Medicine at Stanford University, where he received both an M.D. and a Ph.D. in economics. A co-author of the Great Barrington Declaration, along with Dr. Sunetra Gupta of Oxford University and Dr. Martin Kulldorff of Harvard University—in Great Barrington, Massachusetts. The three of us come from very different disciplinary backgrounds and from very different parts of the political spectrum. Yet we had arrived at the same view—the view that the widespread lockdown policy has been a devastating public health mistake. In response, we wrote and issued the Great Barrington Declaration, which can be viewed—along with explanatory videos, answers to frequently asked questions, a list of co-signers, etc.—online at www.gbdeclaration.org.

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6 Phone Sanitizers You Need To Have Amidst The Pandemic

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We are amidst a full-blown pandemic. While it may be true, we’ve never been in a situation like this before, we can still take control of our surroundings. Scientists tell us to practice effective hygiene, thus the need to sanitize every surface around us. But are we genuinely effective in sanitizing everything that we use daily?

One thing that we always seem to have on our pockets and by our sides are our smartphones. We can often neglect or forget to sanitize our smartphones from all the potential viruses that may be on its surface. Good thing that we have UV phone sanitizers to serve as an answer to the germs and viruses that may be on our phones. 

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AstraZeneca and Johnson & Johnson, vaccine trials are positioned to restart after being paused over potential safety concerns

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the staff of the Ridgewood blog

New Brunswick NJ, according to Johns Hopkins Center for Health Security two major vaccine trials, those of AstraZeneca and Johnson & Johnson, are positioned to restart after being paused over potential safety concerns. The AstraZeneca trial was paused on September 6th, but after independent monitoring of the adverse event several trial sites in other countries resumed later in September. The US FDA held off on restarting AstraZeneca trial sites in the US through October in order to further investigate the event with their own team. The Johnson & Johnson vaccine trial was paused on October 11 after a participant suffered a stroke. This adverse event was also independently reviewed and a final report was sent to the US FDA that recommends the vaccine trial continue. The Johnson & Johnson trial can start re-enrolling participants as early as next week. This vaccine is of particular interest to many since it is a one-dose vaccine which would greatly simplify the process of quickly inoculating millions of people. The AstraZeneca vaccine has already shown promising preliminary results and seems to produce an immunogenic response in elderly participants as well as in younger ones. It is important that any eventual vaccine can produce immunogenic responses in the eldery, in children, and in those with underlying conditions. The Pfizer vaccine has begun to enroll a cohort of children between the ages of 12-18 to test its efficacy in this age group. 16- and 17-year-old volunteers are the first to be enrolled in this study, with researchers soon looking to enroll their younger peers.

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Barack Obama allegedly cautioned another Democrat not to ‘underestimate Joe’s ability to f**k things up’

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the staff of the Ridgewood blog

Ridgewood NJ, radio show host  Mark Simone  some of Joe Biden’s best calls on the pandemic: 

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Governor Cuomo Blasted for Book Touting His Pandemic “Leadership”

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the staff of the Ridgewood blog

New York NY, New York Governor Andrew Cuomo is taking some heat for releasing a book touting his efforts to stop the spread of COVID-19. Never mind that the state of New York lost 33,000 lives to the illness, and over a million residents have lost their jobs.

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56% Americans Say they Are Better Off Now than 4 years Ago

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the staff of the Ridgewood blog

Ridgewood NJ,  Gallup poll taken Sept. 14-28, more than 1,000 Americans were asked “to compare your situation today with what it was four years ago. Are you better off than you were four years ago or not?” Even after 7 months of COVID19 lock downs a whopping 56% said they are better off. Just under a third (32%) said they were not.